Amyloidosis News - October 2021

Early Diagnosis Is Imperative in hATTR/ATTRv with Infiltrative Cardiac Involvement

Improving nurses’ knowledge of specific cardiovascular symptoms may enhance clinical suspicion resulting in early diagnosis of hereditary transthyretin amyloidosis and prompt intervention. Read More ›

Inflammation or Small-Vessel Disease Could Be Responsible for a False-Positive Bone Scintigraphy Signal for Transthyretin Amyloidosis

Early Diagnosis

Endomyocardial biopsy is recommended for TTR cardiac amyloidosis diagnosis in elderly patients, based on false-positive bone scintigraphy case. Read More ›

An Evaluation of Daratumumab-Based Treatment for Immunoglobulin Light-Chain Amyloidosis

Management

Adding daratumumab to bortezomib, cyclophosphamide, and dexamethasone led to higher frequencies of hematologic complete response and survival free from major organ deterioration or hematologic progression in patients with newly diagnosed AL. Read More ›

Risk of Cardiac Involvement in Hereditary Transthyretin Amyloidosis May Be Gender-Biased

Hereditary ATTR

Myocardial involvement was more common and distinct in male patients with variant transthyretin amyloidosis. Read More ›

Early Diagnosis of Cardiac Involvement in Hereditary Transthyretin Amyloidosis Urged

Early Diagnosis

Since newly approved treatments can specifically inhibit further deposition of amyloid material, early diagnosis of cardiac involvement in transthyretin amyloidosis (ATTR) before appearance of left ventricular hypertrophy is advisable. Read More ›

Online First

Value of Referring for Genetic Testing in Diagnosis of ATTRv

Early Diagnosis

Early diagnosis of ATTRv may facilitate early treatment initiation with disease-modifying therapy. Read More ›

Amyloidosis News - October 2021

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