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2021
March 2021
Amyloidosis News - March 2021
Accelerated Approval Granted for Newly Diagnosed Light Chain Amyloidosis Treatment
Clinical Management
The ANDROMEDA study revealed a significant hematologic complete response rate in patients with newly diagnosed light chain amyloidosis treated with daratumumab plus hyaluronidase human-fihj.
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Highlighting Misdiagnosis: Technetium-Pyrophosphate Cardiac Scintigraphy Shows Limits of Transthyretin Amyloid Imaging
Misdiagnosis
Other amyloid subtypes may also cause myocardial pyrophosphate radiotracer uptake, highlighting the need for caution when using noninvasive diagnostic approaches.
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Recognizing Potential Clinical Markers of Hereditary Transthyretin Amyloidosis for Early Diagnosis
Hereditary ATTR
Clinicians need to be aware of potential signals of hereditary transthyretin amyloidosis that most commonly present in the year before diagnosis.
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Tracing the Journey Among Patients with Tc-Pyrophosphate–Positive Transthyretin Cardiac Amyloidosis
Early Diagnosis
Clinical signals and features of positive PYP transthyretin cardiac amyloidosis highlight the need for early diagnosis.
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Prognostic Predictors Based on Echocardiographic Phenotype of Transthyretin Cardia Amyloidosis
Clinical Management
The presence of severe aortic stenosis in the context of transthyretin cardiac amyloidosis is associated with a dramatic reduction in patient survival.
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Top Trending Articles
1.
Evolving Approaches to Transthyretin Stabilization for Cardiac ATTR
2.
Transthyretin (TTR) Protein in Humans: Stabilization vs Destabilization
By
Amy Brownell, MSN, FNP-C, AACC
;
Sarah C. Paciulli, MS, RN, CHFN, NP-C
;
Lori Roth, MS, PA-C
3.
Utility of Functional Assessments in the Prognosis of Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
By
Amy Brownell, MSN, FNP-C, AACC
;
Sarah C. Paciulli, MS, RN, CHFN, NP-C
;
Lori Roth, MS, PA-C
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