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Hereditary ATTR
Association of Val122Ile TTR Variant and HF in Black Individuals
Hereditary ATTR
Amyloidosis News - 2022
Retrospective study finds unfavorable outcomes associated with the Val122Ile TTR variant in black individuals who develop heart failure.
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Late-Onset and Early-Onset Inherited Transthyretin Amyloidosis: Patient Characteristics and Symptoms
Hereditary ATTR
Amyloidosis News - 2022
According to a global registry study, late-onset inherited transthyretin amyloidosis was more likely to be misdiagnosed and to present with more heterogeneous and severe symptoms compared with early-onset disease.
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Genetic Insights May Enhance the Differential Diagnosis and Understanding of Patients with Transthyretin Mutations
Hereditary ATTR
Amyloidosis News - 2022
Recognizing critical differences in genotype and phenotype among patients with transthyretin amyloidosis or other inherited cardiovascular diseases is imperative for optimal outcomes.
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Effect of Mutation Zygosity and Sex on the Range of Transthyretin Cardiac Amyloidosis Disease Severity in 1 Family
Hereditary ATTR
Amyloidosis News - 2022
Providers face challenges with clinical vigilance and treatment for transthyretin amyloidosis due to the range of disease severity and phenotypic penetrance of carriers of variant forms.
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Prevalence of Peripheral Polyneuropathy in Patients with Cardiomyopathy Secondary to Hereditary Transthyretin Amyloidosis and V122I Mutation
Hereditary ATTR
Amyloidosis News - 2022
This study underscores the importance of assessing patients with transthyretin amyloidosis cardiomyopathy and carriers of the V122I mutation for peripheral polyneuropathy.
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Risk of Cardiac Involvement in Hereditary Transthyretin Amyloidosis May Be Gender-Biased
Hereditary ATTR
Amyloidosis News - October 2021
Myocardial involvement was more common and distinct in male patients with variant transthyretin amyloidosis.
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Evaluating Clinicians’ Differential Diagnosis Using Genotypic and Phenotypic Similarities and Differences in Patients with ATTR or Other Inherited CVDs
Hereditary ATTR
Amyloidosis News - August 2021
To accurately diagnose and appropriately manage ATTRv, clinicians need to be aware of red-flag symptoms and recognize the critical value of genetic testing.
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Insights from a Genetic Testing Program into Characteristics of Patients with P.V142I Mutations Associated with Hereditary Transthyretin Amyloidosis
Hereditary ATTR
Amyloidosis News - September 2021
It is essential for clinicians to recognize “red flag” symptoms to diagnose hATTR amyloidosis.
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Retinol Binding Protein 4 (RBP4) May Help Identify Asymptomatic hATTR in V142I Carriers
Hereditary ATTR
Amyloidosis News - July 2021
Plasma biomarkers may help differentiate TTR V142I carriers from noncarriers in young preclinical cases.
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The T60A Variant Is the Most Common Genotype in the Irish Population That Ranges Widely in Clinical Presentation
Hereditary ATTR
Amyloidosis News - May 2021
The T60A variant of hATTR presents with a high prevalence of neurologic manifestations that are more frequent at an earlier stage than cardiac manifestations.
Read More ›
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