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Myocardial Composition Differences Between Patients with Active Disease versus Those in Remission for Cardiac Light Chain Amyloidosis
Clinical Management
Amyloidosis News - 2022
Remission for cardiac light chain amyloidosis for >1 year may be associated with changes in myocardial composition without a reduction in extracellular volume.
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Antibody Responses to COVID-19 Vaccination in Patients with Monoclonal Gammopathies and Light Chain Amyloidosis
Clinical Management
Amyloidosis News - 2022
A new study reports high antibody response rates after COVID-19 vaccination among patients with monoclonal gammopathies of unknown significance, smoldering myeloma, multiple myeloma, or light chain amyloidosis.
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Left Atria in Transthyretin Amyloid Cardiomyopathy: Structural and Functional Involvement
Clinical Management
Amyloidosis News - 2022
As with the ventricles, amyloid infiltration in the atria may affect the severity of transthyretin amyloid cardiomyopathy.
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Response to Daratumumab for Relapsed/Refractory Light Chain Amyloidosis in a Real-World Setting
Clinical Management
Amyloidosis News - 2022
A study examined the hematologic and organ response rates to daratumumab in patients with relapsed/refractory light chain amyloidosis.
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Results from the Phase 3 TOURMALINE-AL1 Trial of Ixazomib plus Dexamethasone for Relapsed/Refractory Light Chain Amyloidosis
Clinical Management
Amyloidosis News - 2022
Ixazomib plus dexamethasone may not improve response rate compared with physician’s choice of care but may delay organ deterioration and mortality in relapsed/refractory light chain amyloidosis.
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Cardiac Resynchronization Therapy in Patients with Cardiac Amyloidosis
Clinical Management
Amyloidosis News - 2022
Results of a recent study suggest that patients with cardiac amyloidosis are less likely to respond to cardiac resynchronization therapy than patients with dilated cardiomyopathy.
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AG10 More Completely Stabilizes TTR Variants That Range in Intrinsic Instability Than Tafamidis
Clinical Management
Amyloidosis News - May 2021
AG10 has the potential to be clinically efficacious in patients with a variety of genotypes associated with both TTR cardiomyopathy and polyneuropathy.
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Treatment with Vutrisiran Reduces Neurologic Impairment and Improves Quality of Life in Patients with Hereditary ATTR Amyloidosis with Polyneuropathy
Clinical Management
Amyloidosis News - April 2021
The HELIOS-A study of vutrisiran in patients with hereditary transthyretin amyloidosis met the primary and all secondary end points.
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Accelerated Approval Granted for Newly Diagnosed Light Chain Amyloidosis Treatment
Clinical Management
Amyloidosis News - March 2021
The ANDROMEDA study revealed a significant hematologic complete response rate in patients with newly diagnosed light chain amyloidosis treated with daratumumab plus hyaluronidase human-fihj.
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Prognostic Predictors Based on Echocardiographic Phenotype of Transthyretin Cardia Amyloidosis
Clinical Management
Amyloidosis News - March 2021
The presence of severe aortic stenosis in the context of transthyretin cardiac amyloidosis is associated with a dramatic reduction in patient survival.
Read More ›
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